New clinical evidence helps explain how soluble corn fibre may support cognitive function

London, UK 17 March  2026: Tate & Lyle PLC (“Tate & Lyle”, “the Company”), a global leader in ingredient solutions for healthier food and beverages, welcomes the publication of a new peer-reviewed study from the University of Illinois Urbana-Champaign, which sheds light on how soluble corn fibre may support cognitive function.

Through a randomised placebo-controlled crossover trial involving healthy middle-aged and older adults, researchers found that daily intake of soluble corn fibre significantly improved focus, while also boosting gut bacteria in ways that may support brain function.

Researchers set out to test whether soluble dietary fibre, already known to support gastrointestinal and physical health, could also improve cognitive performance by changing the gut microbiota, an emerging area of research. The study specifically evaluated the effects of soluble corn fibre on cognitive performance, gut microbiota composition, and the substances those bacteria produce, with the aim of identifying changes in the gut environment affecting cognitive function.

Over a four-week period, forty-two participants consumed soluble corn fibre daily and carried out tests to measure their memory and ability to focus attention. Researchers found that soluble corn fibre consumption led to selectively improved response times during tests compared with the control and increased the abundance of Parabacteroides. Parabacteroides are bacteria that have been linked to possible anti-inflammatory effects, gut barrier protection, and gut derived compounds that could be relevant to gut-brain communication and health outcomes¹.

Dr. David A. Alvarado, lead researcher, University of Illinois Urbana-Champaign, said: “Soluble fibre is well known for supporting gut and overall physical health, but we are still learning how specific fibres might influence the brain. In our study, consuming soluble corn fibre significantly improved how quickly participants responded during tests of attention and inhibitory control, without sacrificing accuracy. We also saw consistent shifts in the gut microbiota, including increases in Parabacteroides distasonis, a microbe that is well suited to break down this fibre. The extent of the cognitive improvement varied with the magnitude of change in Parabacteroides. These findings point to a gut microbiome signal that may partly help explain how soluble corn fibre supports aspects of brain-related performance.” 

Dr. Clare Leonard, VP Nutrition and Health Sciences, Tate & Lyle, said: “There is so much potential for better health outcomes through targeted feeding of the gut microbiota. Fibre is the greatest underutilised resource in our diets. We are seeing studies linking the gut-heart axis, gut-brain axis, and so much more. What’s so wonderful is the solution isn’t an exclusive or expensive supplement but an affordable ingredient that consumers and the industry can easily build into everyday diets: soluble corn fibre. Increasing intakes could be a major unlock for public health.” 

Abigail Storms, VP Sweeteners and Fibres, Tate & Lyle, said: "The science of the gut–brain axis is advancing rapidly, and this study is a powerful example of how nutrition can support cognitive outcomes in ways consumers increasingly care about. Our market insights show strong demand for benefits like focus and stress support, but also a disconnect: people are seeking these outcomes while the industry is still in the early stages of clearly explaining how fibre, prebiotics, and probiotics really work. Evidence that soluble corn fibre can improve focus and positively shift gut bacteria helps bridge that gap, reinforces how everyday ingredients can play a meaningful role in wellbeing. With fibre intakes globally well below recommended levels, connecting this kind of science to consumer-friendly benefits is an important step toward motivating the higher fibre consumption we know is needed.” 
 

The peer-reviewed study has been published in The Journal of Nutrition and was part-funded by Tate & Lyle. The soluble corn fibre used in the study was Tate & Lyle’s PROMITOR® Soluble Fibre. 

ENDS 

Notes to editors 
 

1. References

• Cuffaro B, et al. Characterization of two Parabacteroides distasoniscandidate strains as new live biotherapeutics against obesity. Cells. 2023;12(9):1378.

• Cui Y, Zhang L, Wang X, Yi Y, Shan Y, Liu B, Zhou Y, Lü X. Roles of intestinal Parabacteroides in human health and diseases. FEMS Microbiol Lett. 2022 Aug 29;369(1):fnac072. doi: 10.1093/femsle/fnac072.

• Liang Z, Di N, Li L, Yang D. Gut microbiota alterations reveal potential gut-brain axis changes in polycystic ovary syndrome. J Endocrinol Invest. 2021 Aug;44(8):1727-1737. doi: 10.1007/s40618-020-01481-5. Epub 2021 Jan 2. Wei W, et al. Parabacteroides distasonisuses dietary inulin to suppress NASH via its metabolite pentadecanoic acid. NatMicrobiol. 2023;8(8):1534‑1548.

2. The peer reviewed study has been published in the Journal of Nutrition 
   Effects of Soluble Corn Fiber Consumption on Executive Functions and Gut Microbiota in Middle to Older Age Adults: A Randomized Controlled Crossover Trial - The Journal of Nutrition

3. Participants consumed PROMITOR® Soluble Fibre (22g per day equivalent to 18g fibre) or a maltodextrin placebo control in a beverage for four weeks, separated by a washout

4. The control contained Tate & Lyle’s maltodextrin (MALTOSWEET® Maltodextrin).