Fibre
The effect of polydextrose on fecal bulk and bowel function inmildly constipated healthy adults: a double-blind, placebo-controlled study [2023]
Risso D., Laurie I., Sarkkinen E., Karnik K. The effect of polydextrose on fecalbulk and bowel function in mildly constipated healthy adults: a double-blind, placebo-controlled study. Functional Foods in Health and Disease2023; 13(5): 240-257.
Age-Dependent Prebiotic Effects of Soluble Corn Fiber in M-SHIME® Gut Microbial Ecosystems [2023]
Arroyo MC, Laurie I, Rotsaert C, Marzorati M, Risso D, Karnik K. Age-Dependent Prebiotic Effects of Soluble Corn Fiber in M-SHIME® Gut Microbial Ecosystems. Plant Foods Hum Nutr. 2023 Mar;78(1):213-220. doi: 10.1007/s11130-023-01043-z. Epub 2023 Jan 25. PMID: 36694053; PMCID: PMC9947079.
Estimating the potential public health impact of fibre enrichment: a UK modelling study [2022}
Canene-Adams K, Laurie I, Karnik K, Flynn B, Goodwin W, Pigat S. Estimating the potential public health impact of fibre enrichment: a UK modelling study. Br J Nutr. 2022 Nov 14;128(9):1868-1874. doi: 10.1017/S0007114521004827. Epub 2022 Jan 7. PMID: 34991735; PMCID: PMC9597481.
Moderate intakes of soluble corn fibre or inulin do not cause gastrointestinal discomfort and are well tolerated in healthy children [2022]
Risso, D. Kaczmarczyk, M. Laurie, I. Mah, E. Blonquist, T M. Derrig, L. Karnik, K. Int J Food Sci Nutr. 2022 Dec;73(8):1104-1115. doi: 10.1080/09637486.2022.2133098. Epub 2022 Oct 17.
A Randomized, Double-Blind, Crossover Study to Determine the Available Energy from Soluble Fiber [2020]
Canene-Adams, K., Spence, L., Kolberg, L. W., Karnik, K., Liska, D., & Mah, E. (2020). A Randomized, Double-Blind, Crossover Study to Determine the Available Energy from Soluble Fiber. Journal of the American College of Nutrition, 1-7. doi:10.1080/07315724.2020.1790440
Comparison of the effects of soluble corn fiber and fructooligosaccharides on metabolism, inflammation and gut microbiome of high-fat diet fed mice [2020]
Van Hul, M, Karnik, K, Canene-Adams, K, De Souza, M, Van den Abbeele, P, Marzorati, M, Delzenne, N, Everard, A, Cani, P. “Comparison of the effects of soluble corn fiber and fructooligosaccharides on metabolism, inflammation and gut microbiome of high-fat diet fed mice.” Am J Physiol Endocrinol Metab. 2020 Aug 24. doi: 10.1152/ajpendo.00108.2020
Effect of soluble corn fiber supplementation for 1 year on bone metabolism in children, the MetA-bone trial [2020]
Palacios, C., Trak-Fellermeier, M., Pérez, C., Huffman, F., Suarez, Y. H., Bursac, Z., . . . Weaver, C. (2020). Effect of soluble corn fiber supplementation for 1 year on bone metabolism in children, the MetA-bone trial: Rationale and design. Contemporary Clinical Trials, 95, 106061. doi:10.1016/j.cct.2020.106061
The Role of Soluble Corn Fiber on Glycemic and Insulin Response [2020]
Tan, W. S., Chia, P. F., Ponnalagu, S., Karnik, K., & Henry, C. J. (2020). The Role of Soluble Corn Fiber on Glycemic and Insulin Response. Nutrients, 12(4), 961. doi:10.3390/nu12040961
A review of the characteristics of dietary fibers relevant to appetite and energy intake outcomes in human intervention trials [2017]
Poutanen, K. S., Dussort, P., Erkner, A., Fiszman, S., Karnik, K., Kristensen, M., . . . Mela, D. J. (2017). A review of the characteristics of dietary fibers relevant to appetite and energy intake outcomes in human intervention trials. The American Journal of Clinical Nutrition. doi:10.3945/ajcn.117.157172
Effects of Soluble Corn Fiber Alone or in Synbiotic Combination with Lactobacillus rhamnosus GG and the Pilus-Deficient Derivative GG-PB12 on Fecal Microbiota, Metabolism, and Markers of Immune Function [2017]
Costabile, A., Bergillos-Meca, T., Rasinkangas, P., Korpela, K., Vos, W. M., & Gibson, G. R. (2017). Effects of Soluble Corn Fiber Alone or in Synbiotic Combination with Lactobacillus rhamnosus GG and the Pilus-Deficient Derivative GG-PB12 on Fecal Microbiota, Metabolism, and Markers of Immune Function: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Elderly (Saimes Study). Frontiers in Immunology, 8. doi:10.3389/fimmu.2017.01443
Prebiotic Potential of a Maize-Based Soluble Fibre and Impact of Dose on the Human Gut Microbiota [2016]
Costabile, A. Deaville, E.R., Morales, A.M, Gibson G.R. (2016). Prebiotic Potential of a Maize-Based Soluble Fibre and Impact of Dose on the Human Gut Microbiota. PLoS One, 11(1):e0144457
Soluble corn fiber increases bone calcium retention in postmenopausal women in a dose-dependent manner [2016]
Jakeman, S. A., Henry, C. N., Martin, B. R., Mccabe, G. P., Mccabe, L. D., Jackson, G. S., . . . Weaver, C. M. (2016). Soluble corn fiber increases bone calcium retention in postmenopausal women in a dose-dependent manner: A randomized crossover trial. The American Journal of Clinical Nutrition, 104(3), 837-843. doi:10.3945/ajcn.116.132761
Soluble maize fibre affects short-term calcium absorption in adolescent boys and girls [2014]
Whisner, C. M., Martin, B. R., Nakatsu, C. H., Mccabe, G. P., Mccabe, L. D., Peacock, M., & Weaver, C. M. (2014). Soluble maize fibre affects short-term calcium absorption in adolescent boys and girls: A randomised controlled trial using dual stable isotopic tracers. British Journal of Nutrition, 112(3), 446-456. doi:10.1017/s0007114514000981
Effect of novel fiber ingredients on ileal and total tract digestibility of energy and nutrients in semi-purified diets fed to growing pigs [2013]
Cervantes-Pahm, S. K., Liu, Y., Evans, A., & Stein, H. H. (2013). Effect of novel fiber ingredients on ileal and total tract digestibility of energy and nutrients in semi-purified diets fed to growing pigs. Journal of the Science of Food and Agriculture, 94(7), 1284-1290. doi:10.1002/jsfa.6405
Effect of polydextrose and soluble maize fibre on energy metabolism, metabolic profile and appetite control in overweight men and women [2013]
Konings, E., Schoffelen, P. F., Stegen, J., & Blaak, E. E. (2013). Effect of polydextrose and soluble maize fibre on energy metabolism, metabolic profile and appetite control in overweight men and women. British Journal of Nutrition, 111(1), 111-121. doi:10.1017/s0007114513002183
Gastrointestinal effects of resistant starch, soluble maize fibre and pullulan in healthy adults [2013]
Klosterbuer, A. S., Hullar, M. A., Li, F., Traylor, E., Lampe, J. W., Thomas, W., & Slavin, J. L. (2013). Gastrointestinal effects of resistant starch, soluble maize fibre and pullulan in healthy adults. British Journal of Nutrition, 110(6), 1068-1074. doi:10.1017/s0007114513000019
Polydextrose and Soluble Corn Fiber Increase Five-Day Fecal Wet Weight in Healthy Men and Women [2013]
Timm, D. A., Thomas, W., Boileau, T. W., Williamson-Hughes, P. S., & Slavin, J. L. (2013). Polydextrose and Soluble Corn Fiber Increase Five-Day Fecal Wet Weight in Healthy Men and Women. The Journal of Nutrition, 143(4), 473-478. doi:10.3945/jn.112.170118
Evaluation of digestive tolerance of a soluble corn fibre [2012]
Housez, B., Cazaubiel, M., Vergara, C., Bard, J., Adam, A., Einerhand, A., & Samuel, P. (2012). Evaluation of digestive tolerance of a soluble corn fibre. Journal of Human Nutrition and Dietetics, 25(5), 488-496. doi:10.1111/j.1365-277x.2012.01252.x
Resistant Starch and Pullulan Reduce Postprandial Glucose, Insulin, and GLP-1, but Have No Effect on Satiety in Healthy Humans [2012]
Klosterbuer, A. S., Thomas, W., & Slavin, J. L. (2012). Resistant Starch and Pullulan Reduce Postprandial Glucose, Insulin, and GLP-1, but Have No Effect on Satiety in Healthy Humans. Journal of Agricultural and Food Chemistry, 60(48), 11928-11934. doi:10.1021/jf303083r
Digestive physiological outcomes related to polydextrose and soluble maize fibre consumption by healthy adult men [2011]
Boler, B. M., Serao, M. C., Bauer, L. L., Staeger, M. A., Boileau, T. W., Swanson, K. S., & Fahey, G. C. (2011). Digestive physiological outcomes related to polydextrose and soluble maize fibre consumption by healthy adult men. British Journal of Nutrition, 106(12), 1864-1871. doi:10.1017/s0007114511002388
Fibre research (cont.)
Soluble fibers and resistant starch ameliorate disease activity in interleukin-10-deficient mice with inflammatory bowel disease [2011]
Bassaganya-Riera J, DiGuardo M, Viladomiu M, de Horna A, Sanchez S, Einerhand AW, Sanders L, Hontecillas R. Soluble fibers and resistant starch ameliorate disease activity in interleukin-10-deficient mice with inflammatory bowel disease. J Nutr. 2011 Jul;141(7):1318-25. doi: 10.3945/jn.111.139022. Epub 2011 May 11. PMID: 21562241.
Soluble fiber dextrin and soluble corn fiber supplementation modify indices of health in cecum and colon of Sprague-Dawley rats [2013]
Knapp BK, Bauer LL, Swanson KS, Tappenden KA, Fahey GC Jr, de Godoy MR. Soluble fiber dextrin and soluble corn fiber supplementation modify indices of health in cecum and colon of Sprague-Dawley rats. Nutrients. 2013 Feb 4;5(2):396-410. doi: 10.3390/nu5020396. PMID: 23381099; PMCID: PMC3635201
Soluble Corn Fiber Consumption on Executive Functions and Gut Microbiota in Middle to Older Age Adults: A Randomized Controlled Crossover Trial [2026]
Alvarado DA, Holthaus TA, Martell S,Southey NL, Atallah M, Sarma R, Revilla D, Brown M, Mehta T, Khan NA, Holscher HD. Effects of Soluble Corn Fiber Consumption on Executive Functions and Gut Microbiota in Middle to Older Age Adults: A Randomized Controlled Crossover Trial. J Nutr. 2026 May;156(5):101473. doi: 10.1016/j.tjnut.2026.101473. Epub 2026 Mar 11. PMID: 41825740.
Soluble fiber dextrin enhances the satiating power of beverages [2011]
Monsivais P, Carter BE, Christiansen M, Perrigue MM, Drewnowski A. Soluble fiber dextrin enhances the satiating power of beverages. Appetite. 2011 Feb;56(1):9-14. doi: 10.1016/j.appet.2010.10.010. Epub 2010 Nov 4. PMID: 21056069.
Pre-2011 fibre research
Evaluation of the effect of four fibers on laxation, gastrointestinal tolerance and serum markers in healthy humans [2010]
Stewart ML, Nikhanj SD, Timm DA, Thomas W, Slavin JL. "Evaluation of the effect of four fibers on laxation, gastrointestinal tolerance and serum markers in healthy humans." Ann Nutr Metab. 2010;56(2):91-8. doi: 10.1159/000275962.
Novel Fibers Increase Bone Calcium Content and Strength beyond Efficiency of Large Intestine Fermentation [2010]
Weaver, C. M., Martin, B. R., Story, J. A., Hutchinson, I., & Sanders, L. (2010). Novel Fibers Increase Bone Calcium Content and Strength beyond Efficiency of Large Intestine Fermentation. Journal of Agricultural and Food Chemistry, 58(16), 8952-8957. doi:10.1021/jf904086d
Dietary fibre: An evolving definition? [2009]
Betteridge, V. (2009). Dietary fibre: An evolving definition? Nutrition Bulletin, 34(2), 122-125. doi:10.1111/j.1467-3010.2009.01757.x
The Effect of the Undigested Fraction of Maize Products on the Activity and Composition of the Microbiota Determined in a Dynamicin VitroModel of the Human Proximal Large Intestine [2009]
Maathuis, A., Hoffman, A., Evans, A., Sanders, L., & Venema, K. (2009). The Effect of the Undigested Fraction of Maize Products on the Activity and Composition of the Microbiota Determined in a Dynamicin VitroModel of the Human Proximal Large Intestine. Journal of the American College of Nutrition, 28(6), 657-666. doi:10.1080/07315724.2009.10719798
Effect of Novel Maize-based Dietary Fibers on Postprandial Glycemia and Insulinemia [2008]
Kendall, C. W., Esfahani, A., Hoffman, A. J., Evans, A., Sanders, L. M., Josse, A. R., . . . Potter, S. M. (2008). Effect of Novel Maize-based Dietary Fibers on Postprandial Glycemia and Insulinemia. Journal of the American College of Nutrition, 27(6), 711-718. doi:10.1080/07315724.2008.10719748
Physiological responses to novel carbohydrates as assessed using canine and avian models [2008]
Knapp BK, Parsons CM, Swanson KS, Fahey GC Jr. Physiological responses to novel carbohydrates as assessed using canine and avian models. J Agric Food Chem. 2008 Sep 10;56(17):7999-8006. doi: 10.1021/jf801042b
Glycemic response and metabolizable energy content of the novel maize-based soluble fibers F4-809, 174-810, and F4-810LS using canine and avian models. A744-A744 [2007]
Fastinger, N,Knapp B, Guevara M, Parsons C, Swanson K, Fahey, G. Glycemic response and metabolizable energy content of the novel maize-based soluble fibers F4-809, 174-810, and F4-810LS using canine and avian models. A744-A744. 2007.
Targeting the Gut-Heart Axis Improves Cardiac Remodeling in a Clinical Scale Model of Cardiometabolic Syndrome [2024]
Herisson FM, Cluzel GL, Llopis-Grimalt MA, O'Donovan AN, Koc F, Karnik K, Laurie I, Canene-Adams K, Ross RP, Stanton C, Caplice NM. Targeting the Gut-Heart Axis Improves Cardiac Remodeling in a Clinical Scale Model of Cardiometabolic Syndrome. JACC Basic Transl Sci. 2024 Nov 20;10(1):1-15. doi: 10.1016/j.jacbts.2024.09.004. PMID: 39906593; PMCID: PMC11788474.
Soluble Corn Fiber Increases Calcium Absorption Associated with Shifts in the Gut Microbiome: A Randomized Dose-Response Trial in Free-Living Pubertal Females [2016]
Whisner CM, Martin BR, Nakatsu CH, Story JA, MacDonald-Clarke CJ, McCabe LD, McCabe GP, Weaver CM. Soluble Corn Fiber Increases Calcium Absorption Associated with Shifts in the Gut Microbiome: A Randomized Dose-Response Trial in Free-Living Pubertal Females. J Nutr. 2016 Jul;146(7):1298-306. doi: 10.3945/jn.115.227256. Epub 2016 Jun 8. PMID: 27281813.
Study on the postprandial blood glucose suppression effect of D-psicose in borderline diabetes and the safety of long-term ingestion by normal human subjects [2010]
Hayashi N, Iida T, Yamada T, Okuma K, Takehara I, Yamamoto T, Yamada K, Tokuda M. Study on the postprandial blood glucose suppression effect of D-psicose in borderline diabetes and the safety of long-term ingestion by normal human subjects. Biosci Biotechnol Biochem. 2010;74(3):510-9. doi: 10.1271/bbb.90707. Epub 2010 Mar 7. PMID: 20208358.
Estimation of maximum non-effect level of D-psicose in causing diarrhea in human subjects [2007]
Iida T, Kishimoto Y, Yoshikawa Y, Okuma K, Yagi K, Matsuo T and Izumori K. Estimation of maximum non-effect level of D-psicose in causing diarrhea in human subjects. Journal of Japanese Council for Advanced Food Ingredients Research. 2007. 10, 10-15.
d-Allulose and erythritol increase butyrate production and impact the gut microbiota in healthy adults and adults with type-2 diabetes ex vivo [2025]
Adolphus K, Van den Abbeele P, Poppe J, Deyaert S, Baudot A, Laurie I, Karnik K, Risso D. d-Allulose and erythritol increase butyrate production and impact the gut microbiota in healthy adults and adults with type-2 diabetes ex vivo. Benef Microbes. 2025 Apr 10;16(5):573-591. doi: 10.1163/18762891-bja00071. PMID: 40312039.
Gastrointestinal tolerance of D-allulose in children: an acute, randomised, double-blind, placebo-controlled, cross-over study [2024]
Risso D, DunnGalvin G, Saxena S, Doolan A, Spence L, Karnik K. Gastrointestinal tolerance of D-allulose in children: an acute, randomised, double-blind, placebo-controlled, cross-over study. Food Funct. 2024 Jan 2;15(1):411-418. doi: 10.1039/d3fo04210c. PMID: 38099623.
Does sweetness exposure drive 'sweet tooth'? [2024]
Mela DJ, Risso D. Does sweetness exposure drive 'sweet tooth'? Br J Nutr. 2024 Jun 14;131(11):1934-1944. doi: 10.1017/S0007114524000485. Epub 2024 Feb 26. PMID: 38403648.
Low-no-calorie sweeteners exert marked compound-specific impact on the human gut microbiota ex vivo [2023]
Van den Abbeele P, Poppe J, Deyaert S, Laurie I, Otto Gravert TK, Abrahamsson A, Baudot A, Karnik K, Risso D. Low-no-calorie sweeteners exert marked compound-specific impact on the human gut microbiota ex vivo. Int J Food Sci Nutr. 2023 Sep;74(5):630-644. doi: 10.1080/09637486.2023.2240037. Epub 2023 Aug 3. PMID: 37537786.
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